Endocrine Abstracts

Background and aims: HbA1c as a gold-standard measure for glycaemic control has been criticized for several years: lacking the ability to capture hypoglycaemia, time spent in different glucose ranges or to reflect glycaemic variability (GV) are frequently reported shortcomings. Continuous glucose monitoring (CGM) can overcome this, and several new CGM-derived parameters have been proposed to provide additional insights, with the concept of time in range (TIR) and other paramet...

Background: Obesity induced inflammation is a key component in the pathogenesis of insulin resistance (IR). In addition, obesity-related non-alcoholic fatty liver disease (NAFLD) also seems to contribute to IR development. Until now, however, it is unclear which, if any component of NAFLD specifically associates with IR. Therefore, the aim is to assess if individual components of NAFLD contribute to IR in obese patients undergoing gastric bypass surgery (GBS).<p class="abs...

Background and Aims: Incorrect injection technique can cause lipohypertrophy resulting in unpredictable insulin release. We aimed to assess the impact of a correct injection technique and lipohypertrophy on HbA1c, hypoglycemia and glucose variability.Methods: 171 insulin-injecting people with diabetes were prospectively evaluated for 6 months. 146 subjects completed the study (75 type 1, 71 type 2). They were provided extensive education concerning injec...